A simple cell-free enzymatic platform for large-scale DNA manufacturing

DNA is not only the foundation of life. It’s also the foundation of modern medicine.

At LineaRx, an Applied DNA Sciences, Inc. (NASDAQ: APDN) company, we have a single purpose – to produce therapeutic DNA faster, of higher purity, and with greater scalability than current methods.

Therapeutic DNA is currently manufactured primarily via plasmids (pDNA), a complex biological method that has remained mostly unchanged for almost 40 years.

Our LinearDNA™ platform is a novel, enzymatic DNA manufacturing approach capable of producing high-quality DNA for nucleic acid-based therapies, including mRNA, Cellular and Gene Therapy and DNA Vaccines. We have named the resultant therapeutic DNA ‘LinearDNA’ or ‘linDNA’.

Our enzymatic approach and deep expertise in polymerase chain reaction (PCR) can dramatically accelerate innovation in nucleic acid-based therapies across a product lifecycle, from research and development to the clinic and commercial manufacturing.

The next generation of therapies require a next generation supply of DNA.