via use of the Linea IVT Platform | Chemically-Modified, Enzymatically-Produced IVT Templates + a Next-Generation RNA Polymerase
Yuhua Sun | Huan Dong | Qiang Zhao | Finly Philip | Clay Shorrock | Aaron Chung | James Hayward
- Linea™ IVT Overview
The Linea IVT Platform is a next generation IVT platform comprised of two components:
(i) chemically modified PCR-produced Linea™ DNA IVT templates; and (ii) Linea RNAP, a novel
high fidelity RNA polymerase linked to a DNA binding domain. Linea IVT allows mRNA producers
to manufacture better mRNA, faster via simplified workflows and reduced double-stranded RNA
(dsRNA) contamination.
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