Accelerating Genetic Engineering and Therapeutic Advancements
Gene editing is transforming the landscape of medicine, enabling precise modifications to DNA for therapeutic interventions, disease modeling, and advanced genetic research. The foundation of successful gene editing relies on high-fidelity DNA templates that drive accurate and efficient genome modifications. LineaRx, an Applied DNA Sciences, Inc. company, delivers a next-generation solution with LineaDNA, an enzymatically-produced alternative to plasmid-based DNA manufacturing.
Enhancing Precision in Gene Editing
Successful gene editing depends on high-quality DNA templates that support both homology-directed repair (HDR) and non-homologous end joining (NHEJ) pathways. LineaDNA offers key advantages for CRISPR, TALENs, and other genome editing technologies.
The LineaDNA Advantage for Gene Editing
Blunt-Ended DNA Templates
Our enzymatic production process generates high-fidelity, blunt-ended DNA essential for precise HDR, ensuring targeted genetic modifications with high efficiency.
Single and Double-Stranded DNA
Whether for small insertions, large gene corrections, or complex gene knock-ins, LineaDNA is available in formats tailored to diverse editing applications.
Minimized Off-Target Risks
LineaDNA enhances safety and reduces the risk of immune responses by eliminating bacterial backbone elements, antibiotic resistance genes, and unwanted sequences.
Gene editing has the potential to revolutionize the treatment of genetic disorders, cancers, and infectious diseases.
Enabling a New Era of Vaccine Innovation
Rapid Clinical Research
The rapid manufacturing process shortens drug discovery timelines, allowing therapies to advance more quickly.
Safety and Efficacy
With its high-purity design, LineaDNA minimizes risks associated with off-target effects and immune activation.
Scalable Development
Whether for ex vivo or in vivo applications, LineaDNA’s streamlined production supports the transition from research to commercial-scale applications.
LineaRx is redefining the possibilities of gene editing and genetic engineering with its innovative LineaDNA platform. By delivering a faster, purer, and more scalable alternative to traditional plasmid-based DNA, we empower scientists and biotech companies to push the boundaries of genomic medicine. With LineaDNA, the future of precise and effective gene editing is within reach.